A large palindrome with interchromosomal gene duplications in the pericentromeric region of the D. melanogaster Y chromosome.

ABSTRACT: The non-recombining Y chromosome is expected to degenerate over evolutionary time, however, gene gain is a common feature of Y chromosomes of mammals and Drosophila. Here, we report that a large palindrome containing interchromosomal segmental duplications is located in the vicinity of the first amplicon detected in the Y chromosome of D. melanogaster. The recent appearance of such amplicons suggests that duplications to the Y chromosome, followed by the amplification of the segmental duplications, are a mechanism for the continuing evolution of Drosophila Y chromosomes.

SUBMITTER: Mendez-Lago M 

PROVIDER: S-EPMC4202384 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature