Noninvasive stimulation of prefrontal cortex strengthens existing episodic memories and reduces forgetting in the elderly.

ABSTRACT: Memory consolidation is a dynamic process. Reactivation of consolidated memories by a reminder triggers reconsolidation, a time-limited period during which existing memories can be modified (i.e., weakened or strengthened). Episodic memory refers to our ability to recall specific past events about what happened, including where and when. Difficulties in this form of long-term memory commonly occur in healthy aging. Because episodic memory is critical for daily life functioning, the development of effective interventions to reduce memory loss in elderly individuals is of great importance. Previous studies in young adults showed that the dorsolateral prefrontal cortex (DLPFC) plays a causal role in strengthening of verbal episodic memories through reconsolidation. The aim of the present stud

SUBMITTER: Sandrini M 

PROVIDER: S-EPMC4202785 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature