Age-related increase in brain activity during task-related and -negative networks and numerical inductive reasoning.

ABSTRACT:

Objective

Recent neuroimaging studies have shown that elderly adults exhibit increased and decreased activation on various cognitive tasks, yet little is known about age-related changes in inductive reasoning.

Methods

To investigate the neural basis for the aging effect on inductive reasoning, 15 young and 15 elderly subjects performed numerical inductive reasoning while in a magnetic resonance (MR) scanner.

Results

Functional magnetic resonance imaging (fMRI) analysis revealed that numerical inductive reasoning, relative to rest, yielded multiple frontal, temporal, parietal, and some subcortical area activations for both age groups. In addition, the younger participants showed significant regions of task-induced deactivation, while no deactivation occurred in the eld

SUBMITTER: Sun L 

PROVIDER: S-EPMC4203211 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature