A chemoselective route to β-enamino esters and thioesters.

ABSTRACT: Conditions were developed for syntheses of β-enamino esters, thioesters, and amides. These reactions involve hydroxybenzotriazole derivatives in buffered media. Illustrative syntheses of some heterocyclic systems are given, including some related to protein-protein interface mimics.

SUBMITTER: Xin D 

PROVIDER: S-EPMC4203388 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature