A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome.

ABSTRACT: The Arabidopsis genome contains numerous large duplicated chromosomal segments, but the different approaches used in previous analyses led to different interpretations regarding the number and timing of ancestral large-scale duplication events. Here, using more appropriate methodology and a more recent version of the genome sequence annotation, we investigate the scale and timing of segmental duplications in Arabidopsis. We used protein sequence similarity searches to detect duplicated blocks in the genome, used the level of synonymous substitution between duplicated genes to estimate the relative ages of the blocks containing them, and analyzed the degree of overlap between adjacent duplicated blocks. We conclude that the Arabidopsis lineage underwent at least two distinct episodes of dup

SUBMITTER: Blanc G 

PROVIDER: S-EPMC420368 | biostudies-literature | 2003 Feb

REPOSITORIES: biostudies-literature