The association between selenium and other micronutrients and thyroid cancer incidence in the NIH-AARP Diet and Health Study.

ABSTRACT:

Background

Selenium is an essential trace element that is important for thyroid hormone metabolism and has antioxidant properties which protect the thyroid gland from oxidative stress. The association of selenium, as well as intake of other micronutrients, with thyroid cancer is unclear.

Methods

We evaluated associations of dietary selenium, beta-carotene, calcium, vitamin D, vitamin C, vitamin E, folate, magnesium, and zinc intake with thyroid cancer risk in the National Institutes of Health - American Association of Retired Persons Diet and Health Study, a large prospective cohort of 566,398 men and women aged 50-71 years in 1995-1996. Multivariable-adjusted Cox proportional hazards regression was used to examine associations between dietary intake of micronutrients, asses

SUBMITTER: O'Grady TJ 

PROVIDER: S-EPMC4203851 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature