Methods of analysis of enteropathogen infection in the MAL-ED Cohort Study.

ABSTRACT: Studies of diarrheal etiology in low- and middle-income countries have typically focused on children presenting with severe symptoms to health centers and thus are best equipped to describe the pathogens capable of leading to severe diarrheal disease. The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) cohort study was designed to evaluate, via intensive community surveillance, the hypothesis that repeated exposure to enteropathogens has a detrimental effect on growth, vaccine response, and cognitive development, which are the primary outcome measures for this study. In the setting of multiple outcomes of interest, a longitudinal cohort design was chosen. Because many or even the majority of enter

SUBMITTER: Platts-Mills JA 

PROVIDER: S-EPMC4204610 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature