Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework.

ABSTRACT: Individuals in the developing world live in conditions of intense exposure to enteric pathogens due to suboptimal water and sanitation. These environmental conditions lead to alterations in intestinal structure, function, and local and systemic immune activation that are collectively referred to as environmental enteropathy (EE). This condition, although poorly defined, is likely to be exacerbated by undernutrition as well as being responsible for permanent growth deficits acquired in early childhood, vaccine failure, and loss of human potential. This article addresses the underlying theoretical and analytical frameworks informing the methodology proposed by the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Developm

SUBMITTER: Kosek M 

PROVIDER: S-EPMC4204611 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature