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Citalopram versus other anti-depressive agents for depression.


ABSTRACT:

Background

Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted some differences in efficacy between second-generation antidepressants. Citalopram, one of the first selective serotonin reuptake inhibitors (SSRI) introduced in the market, is one of these antidepressant drugs that clinicians use for routine depression care.

Objectives

To assess the evidence for the efficacy, acceptability and tolerability of citalopram in comparison with tricyclics, heterocyclics, other SSRIs and other conventional and non-conventional antidepressants in the acute-phase treatment of major depressi

SUBMITTER: Cipriani A 

PROVIDER: S-EPMC4204633 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature