Identification of antigenic proteins of the nosocomial pathogen Klebsiella pneumoniae.

ABSTRACT: The continuous expansion of nosocomial infections around the globe has become a precarious situation. Key challenges include mounting dissemination of multiple resistances to antibiotics, the easy transmission and the growing mortality rates of hospital-acquired bacterial diseases. Thus, new ways to rapidly detect these infections are vital. Consequently, researchers around the globe pursue innovative approaches for point-of-care devices. In many cases the specific interaction of an antigen and a corresponding antibody is pivotal. However, the knowledge about suitable antigens is lacking. The aim of this study was to identify novel antigens as specific diagnostic markers. Additionally, these proteins might be aptly used for the generation of vaccines to improve current treatment options. H

SUBMITTER: Hoppe S 

PROVIDER: S-EPMC4205017 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature