Brain imaging findings in elderly adults and years of life, healthy life, and able life over the ensuing 16 years: the Cardiovascular Health Study.

ABSTRACT:

Objectives

To determine whether elderly people with different patterns of magnetic resonance imaging (MRI) findings have different long-term outcomes.

Design

Longitudinal cohort study.

Setting

Cardiovascular Health Study.

Participants

Individuals aged 65 and older were recruited (N = 5,888); 3,660 of these underwent MRI, and 3,230 without a stroke before MRI were included in these analyses.

Measurements

Cluster analysis of brain MRI findings was previously used to define five clusters: normal, atrophy, simple infarct, leukoaraiosis, and complex infarct. Participants were subsequently classified as healthy if they rated their health as excellent, very good, or good and as able if they did not report any limitations in activities of daily living (ADLs). Me

SUBMITTER: Longstreth WT 

PROVIDER: S-EPMC4205483 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature