Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases.

ABSTRACT: Brain stimulation, a therapy increasingly used for neurological and psychiatric disease, traditionally is divided into invasive approaches, such as deep brain stimulation (DBS), and noninvasive approaches, such as transcranial magnetic stimulation. The relationship between these approaches is unknown, therapeutic mechanisms remain unclear, and the ideal stimulation site for a given technique is often ambiguous, limiting optimization of the stimulation and its application in further disorders. In this article, we identify diseases treated with both types of stimulation, list the stimulation sites thought to be most effective in each disease, and test the hypothesis that these sites are different nodes within the same brain network as defined by resting-state functional-connectivity MRI. Sit

SUBMITTER: Fox MD 

PROVIDER: S-EPMC4205651 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature