Investigating inhibitory control in children with epilepsy: an fMRI study.

ABSTRACT:

Objective

Deficits in executive function are noted increasingly in children with epilepsy and have been associated with poor academic and psychosocial outcomes. Impaired inhibitory control contributes to executive dysfunction in children with epilepsy; however, its neuroanatomic basis has not yet been investigated. We used functional magnetic resonance imaging (fMRI) to probe the integrity of activation in brain regions underlying inhibitory control in children with epilepsy.

Methods

This cross-sectional study consisted of 34 children aged 8-17 years: 17 with well-controlled epilepsy and 17 age- and sex-matched controls. Participants performed the antisaccade (AS) task, representative of inhibitory control, during fMRI scanning. We compared AS performance during neutral and

SUBMITTER: Triplett RL 

PROVIDER: S-EPMC4206566 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature