Dataset Information
Combined magnetic nanoparticle-based microRNA and hyperthermia therapy to enhance apoptosis in brain cancer cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Yin PT
PROVIDER: S-EPMC4206574 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Publications
Combined magnetic nanoparticle-based microRNA and hyperthermia therapy to enhance apoptosis in brain cancer cells.
Small (Weinheim an der Bergstrasse, Germany) 20140620 20
A novel therapy is demonstrated utilizing magnetic nanoparticles for the dual purpose of delivering microRNA and inducing magnetic hyperthermia. In particular, the combination of lethal-7a microRNA (let-7a), which targets a number of the survival pathways that typically limit the effectiveness of hyperthermia, with magnetic hyperthermia greatly enhances apoptosis in brain cancer cells. ...[more]