Maternal hyperglycemia during pregnancy predicts adiposity of the offspring.

ABSTRACT:

Objective

To investigate associations between maternal pregnancy hyperglycemia, gestational diabetes mellitus (GDM), and offspring adiposity.

Research design and methods

We evaluated these associations in a longitudinal study of 421 mother-daughter pairs at Kaiser Permanente Northern California. Maternal pregnancy glucose values were obtained from maternal medical records. Outcomes included three measures of girls' adiposity, measured annually: (1) ≥85th age-specific percentile for BMI; (2) percent body fat (%BF); and (3) waist-to-height ratio (WHR).

Results

Adjusting for maternal age at delivery, race/ethnicity, pregravid BMI, girl's age, and girl's age at onset of puberty, having a mother with GDM increased a girl's risk of having a BMI ≥85th percentile or having %B

SUBMITTER: Kubo A 

PROVIDER: S-EPMC4207207 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature