Irritable bowel syndrome and chronic fatigue 6 years after giardia infection: a controlled prospective cohort study.

ABSTRACT:

Background

Functional gastrointestinal disorders and fatigue may follow acute infections. This study aimed to estimate the persistence, prevalence, and risk of irritable bowel syndrome and chronic fatigue 6 years after Giardia infection.

Methods

We performed a controlled prospective study of a cohort of 1252 individuals who had laboratory-confirmed Giardia infection during a waterborne outbreak in 2004. In total, 748 cohort cases (exposed) and 878 matched controls responded to a postal questionnaire 6 years later (in 2010). Responses were compared to data from the same cohort 3 years before (in 2007).

Results

The prevalences of irritable bowel syndrome (39.4%) by Rome III criteria and chronic fatigue (30.8%) in the exposed group 6 years after giardiasis were significa

SUBMITTER: Hanevik K 

PROVIDER: S-EPMC4207419 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature