Impact of treatment site in adolescents and young adults with central nervous system tumors.

ABSTRACT:

Background

Adolescents and young adults (AYAs; aged 15-39 years) have inferior survival in comparison with younger (aged 0-14 years) cancer patients. Impact of care at specialized centers such as National Cancer Institute-designated Comprehensive Cancer Centers (NCICCC) for AYAs of all ages or the Children's Oncology Group (COG) for AYAs aged 15 to 21 years with central nervous system (CNS) tumors remains unstudied.

Methods

We constructed a cohort of 560 children and 784 AYAs with CNS tumors reported to the Los Angeles cancer registry from 1998 to 2008. Cox and logistic regression models were used, with two-sided P values from Wald χ(2) tests.

Results

In Cox regression analysis restricted to World Health Organization (WHO) grade II tumors, patients of all ages saw wor

SUBMITTER: Wolfson J 

PROVIDER: S-EPMC4207868 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature