Cognitive function after the initiation of adjuvant endocrine therapy in early-stage breast cancer: an observational cohort study.

ABSTRACT:

Purpose

This report examines cognitive complaints and neuropsychological (NP) testing outcomes in patients with early-stage breast cancer after the initiation of endocrine therapy (ET) to determine whether this therapy plays any role in post-treatment cognitive complaints.

Patients and methods

One hundred seventy-three participants from the Mind Body Study (MBS) observational cohort provided data from self-report questionnaires and NP testing obtained at enrollment (T1, before initiation of ET), and 6 months later (T2). Bivariate analyses compared demographic and treatment variables, cognitive complaints, depressive symptoms, quality of life, and NP functioning between those who received ET versus not. Multivariable linear regression models examined predictors of cognitive c

SUBMITTER: Ganz PA 

PROVIDER: S-EPMC4209106 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature