Gender differences, clinical correlates, and longitudinal outcome of bipolar disorder with comorbid migraine.

ABSTRACT:

Objective

Migraine is a common comorbidity of bipolar disorder and is more prevalent in women than men. We hypothesized comorbid migraine would be associated with features of illness and psychosocial risk factors that would differ by gender and impact outcome.

Method

A retrospective analysis was conducted to assess association between self-reported, physician-diagnosed migraine, clinical variables of interest, and mood outcome in subjects with DSM-IV bipolar disorder (N = 412) and healthy controls (N = 157) from the Prechter Longitudinal Study of Bipolar Disorder, 2005-2010. Informed consent was obtained from all participants.

Results

Migraine was more common in subjects with bipolar disorder (31%) than in healthy controls (6%) and had elevated risk in bipolar disorde

SUBMITTER: Saunders EF 

PROVIDER: S-EPMC4211932 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature