Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study.

ABSTRACT:

Background

Guidelines and experts describe 5% to 10% reductions in body weight as 'clinically important'; however, it is not clear if 5% to 10% weight reductions correspond to clinically important improvements in health-related quality of life (HRQL). Our objective was to calculate the amount of weight loss required to attain established minimal clinically important differences (MCIDs) in HRQL, measured using three validated instruments.

Methods

Data from the Alberta Population-based Prospective Evaluation of Quality of Life Outcomes and Economic Impact of Bariatric Surgery (APPLES) study, a population-based, prospective Canadian cohort including 150 wait-listed, 200 medically managed and 150 surgically treated patients were examined. Two-year changes in weight and HRQL meas

SUBMITTER: Warkentin LM 

PROVIDER: S-EPMC4212133 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature