When study site contributes to outcomes in a multi-center randomized trial: a secondary analysis of decisional conflict in men with localized prostate cancer.

ABSTRACT:

Purpose

Evaluate baseline factors that may explain the influence of study site on decisional conflict (DC) in men from the Personal Patient Profile: Prostate (P3P) randomized trial.

Materials and methods

476 cases from 5 P3P sites were included. Participants completed baseline demographic assessments, 4 subscales of the DC scale at baseline (uncertainty, informed, values clarity, and support), the Expanded Prostate Cancer Index Composite (short form) and the State-Trait Anxiety Inventory. Site data regarding typical practices were collected. Linear regressions were used to model the relation between baseline DC scores and study site adjusting for the list of variables.

Results

Baseline decisional uncertainly (p = 0.001) and informed (p = 0.03) subscales were significa

SUBMITTER: Underhill ML 

PROVIDER: S-EPMC4213457 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature