Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy.

ABSTRACT: Multimodal imaging-guided photothermal therapy (PTT), for the therapy of cancer, based on a ferritin (FRT) nanocage loaded with the near-infrared dye IR820 (designated DFRT) is demonstrated. The dual roles of DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm for high quantum-yield fluorescence imaging on the one hand and 808 nm for photoacoustic imaging and PTT with high photothermal conversion efficiency on the other.

SUBMITTER: Huang P 

PROVIDER: S-EPMC4215197 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature