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Comprehensive analysis of DNA methylation data with RnBeads.

ABSTRACT: RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association studies and epigenetic biomarker discovery in cancer cohorts.

SUBMITTER: Assenov Y 

PROVIDER: S-EPMC4216143 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature

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Comprehensive analysis of DNA methylation data with RnBeads.

Assenov Yassen Y   Müller Fabian F   Lutsik Pavlo P   Walter Jörn J   Lengauer Thomas T   Bock Christoph C  

Nature methods 20140928 11

RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association stu  ...[more]

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