Asthma status and waning of measles antibody concentrations after measles immunization.

ABSTRACT:

Background

Asthmatics have increased risks of common and serious microbial infections including vaccine preventable diseases. Little is known about whether asthma influences waning of humoral immunity. We assessed whether asthma status influences waning of anti-measles virus antibody concentrations over time.

Methods

The study used a cross-sectional study cohort of healthy children who had been immunized with 1 dose of MMR-II at age approximately 15 months. Between 5 and 12 years of age, measles vaccine virus-specific antibody (IgG) values were measured by enzyme immunoassay and considered seropositive if the enzyme immunoassay index unit was ≥ 1. The medical records were reviewed to determine asthma status during the first 18 years of life by applying predetermined criteria

SUBMITTER: Yoo KH 

PROVIDER: S-EPMC4216609 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature