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Visceral leishmaniasis due to Leishmania infantum with renal involvement in HIV-infected patients.


ABSTRACT:

Background

We describe histological, clinical findings and outcomes of renal involvement during Leishmania infantum infection in four HIV-infected patients in South France and North Italy hospital settings.

Cases presentation

Four HIV-infected Caucasian patients (age 24-49) performed renal biopsy during episodes of visceral leishmaniasis. They presented severe immunosuppression, frequent relapses of visceral leishmaniasis during a follow-up period of several years and partial or complete recovery of renal function after anti-parasitic treatment. Main clinical presentations were nephrotic or nephritic syndrome and/or acute renal failure secondary to membranoproliferative type III glomerulonephritis or acute interstitial nephritis. Clinical outcome was poor, probably as a cons

SUBMITTER: Vassallo M 

PROVIDER: S-EPMC4216653 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature