The safety and efficacy of irreversible electroporation for the ablation of prostate cancer: a multicentre prospective human in vivo pilot study protocol.

ABSTRACT:

Introduction

Current surgical and ablative treatment options for prostate cancer have a relatively high incidence of side effects, which may diminish the quality of life. The side effects are a consequence of procedure-related damage of the blood vessels, bowel, urethra or neurovascular bundle. Ablation with irreversible electroporation (IRE) has shown to be effective in destroying tumour cells and harbours the advantage of sparing surrounding tissue and vital structures. The aim of the study is to evaluate the safety and efficacy and to acquire data on patient experience of minimally invasive, transperineally image-guided IRE for the focal ablation of prostate cancer.

Methods and analysis

In this multicentre pilot study, 16 patients with prostate cancer who are scheduled fo

SUBMITTER: van den Bos W 

PROVIDER: S-EPMC4216863 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature