Individualising dual antiplatelet therapy after percutaneous coronary intervention: the IDEAL-PCI registry.

ABSTRACT:

Objective

To evaluate the clinical utility of individualising dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in an all-comers population, including ST-elevation myocardial infarction (STEMI) patients.

Setting

Tertiary care single centre registry.

Participants

1008 consecutive PCI patients with stent implantation, without exclusion criteria.

Intervention

Peri-interventional individualisation of DAPT, guided by multiple electrode aggregometry (MEA), to overcome high on-treatment platelet reactivity (HPR) to ADP-induced (≥50 U) and arachidonic acid (AA)-induced aggregation (>35 U).

Outcome measures

The primary efficacy end point was definite stent thrombosis (ST) at 30 days. The primary safety end point was thrombolysis in m

SUBMITTER: Christ G 

PROVIDER: S-EPMC4216867 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature