Percutaneous image-guided biopsy for non-mass-forming isolated splenomegaly and suspected malignant lymphoma.

ABSTRACT:

Background

The aim of this study was to evaluate the accuracy, safety, and role of splenic biopsy in the management of patients with non-mass-forming isolated splenomegaly and suspected malignant lymphoma.

Methods

Between 2001 and 2013, 137 biopsies were performed under computed tomography (CT) fluoroscopic guidance in 39 patients. All patients had splenomegaly based on the CT findings and a suspected diagnosis of malignant lymphoma based on their clinical symptoms. The spleen was the only accessible site to perform a biopsy, and no mass lesions could be identified in the spleen.

Results

The overall sensitivity, specificity, and diagnostic accuracy of image-guided biopsy for malignant lymphoma were 88%, 100% and 92%, respectively. Major complications occurred in 3 pat

SUBMITTER: Tokue H 

PROVIDER: S-EPMC4218790 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature