Graphene-based carbon-layered electrode array technology for neural imaging and optogenetic applications.

ABSTRACT: Neural micro-electrode arrays that are transparent over a broad wavelength spectrum from ultraviolet to infrared could allow for simultaneous electrophysiology and optical imaging, as well as optogenetic modulation of the underlying brain tissue. The long-term biocompatibility and reliability of neural micro-electrodes also require their mechanical flexibility and compliance with soft tissues. Here we present a graphene-based, carbon-layered electrode array (CLEAR) device, which can be implanted on the brain surface in rodents for high-resolution neurophysiological recording. We characterize optical transparency of the device at >90% transmission over the ultraviolet to infrared spectrum and demonstrate its utility through optical interface experiments that use this broad spectrum transpar

SUBMITTER: Park DW 

PROVIDER: S-EPMC4218963 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature