Epidemiology of bloodstream infections in patients with acute myeloid leukemia undergoing levofloxacin prophylaxis.

ABSTRACT:

Background

Infections are a common cause of morbidity and mortality in patients with acute myeloid leukemia (AML). The evidence for efficacy of antibiotic prophylaxis in reducing the mortality rates and the incidence of bacterial infections was also reported by a systematic review published by Cochrane in 2012. The objective of our study was to report the incidence and the etiology of bloodstream infections in patients with AML undergoing levofloxacin prophylaxis during neutropenic episodes.

Methods

This was a retrospective study of patients with diagnosis of AML during 2001-2007.

Results

A total of 81 patients were included in the study. Two hundred and ninetyone neutropenic episodes were studied, of which 181 were febrile. Bacteria isolated from blood cultures were

SUBMITTER: De Rosa FG 

PROVIDER: S-EPMC4219399 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature