Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis.

ABSTRACT:

Objectives

To examine the safety and effectiveness of cobalt-chromium everolimus eluting stents compared with bare metal stents.

Design

Individual patient data meta-analysis of randomised controlled trials. Cox proportional regression models stratified by trial, containing random effects, were used to assess the impact of stent type on outcomes. Hazard ratios with 95% confidence interval for outcomes were reported.

Data sources and study selection

Medline, Embase, the Cochrane Central Register of Controlled Trials. Randomised controlled trials that compared cobalt-chromium everolimus eluting stents with bare metal stents were selected. The principal investigators whose trials met the inclusion criteria provided data for individual patients.

Primary outcomes

The

SUBMITTER: Valgimigli M 

PROVIDER: S-EPMC4220288 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature