Comparative effectiveness of digoxin and propranolol for supraventricular tachycardia in infants.

ABSTRACT:

Objectives

Supraventricular tachycardia is the most common arrhythmia in infants, and antiarrhythmic medications are frequently used for prophylaxis. The optimal prophylactic antiarrhythmic medication is unknown, and prior randomized trials have been underpowered. We used data from a large clinical registry to compare efficacy and safety of digoxin and propranolol for infant supraventricular tachycardia prophylaxis. We hypothesized that supraventricular tachycardia recurrence is less common on digoxin when compared with propranolol.

Design

Retrospective cohort study.

Setting

Pediatrix Medical Group neonatal ICUs.

Patients

Infants discharged from 1998 to 2012 with supraventricular tachycardia who were treated with digoxin or propranolol. We excluded infants disc

SUBMITTER: Hornik CP 

PROVIDER: S-EPMC4221410 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature