Improvements to pairwise sequence comparison (PASC): a genome-based web tool for virus classification.

ABSTRACT: The number of viral genome sequences in the public databases is increasing dramatically, and these sequences are playing an important role in virus classification. Pairwise sequence comparison is a sequence-based virus classification method. A program using this method calculates the pairwise identities of virus sequences within a virus family and displays their distribution, and visual analysis helps to determine demarcations at different taxonomic levels such as strain, species, genus and subfamily. Subsequent comparison of new sequences against existing ones allows viruses from which the new sequences were derived to be classified. Although this method cannot be used as the only criterion for virus classification in some cases, it is a quantitative method and has many advantages over co

SUBMITTER: Bao Y 

PROVIDER: S-EPMC4221606 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature