The incidence and risk factors of acute kidney injury after hepatobiliary surgery: a prospective observational study.

ABSTRACT:

Background

Although intraperitoneal surgery is a major operation associated with postoperative acute kidney injury (AKI), the incidence, risk factors, and long-term renal outcome are not well known. We aimed to determine the risk factors and 6 months renal outcome in patients with clinical or subclinical AKI after hepatobiliary surgery. We also assessed the validity of urine neutrophil gelatinase-associated lipocalin (NGAL) in the early detection of AKI or prediction of renal outcome.

Methods

This prospective observational study enrolled patients with normal renal function who underwent hepatobiliary surgeries. Urine and serum samples were collected for NGAL measurement.

Results

Among 131 patients, 10 (7.6%) developed postoperative AKI. Urine NGAL at 12 h postsurgery

SUBMITTER: Cho E 

PROVIDER: S-EPMC4221681 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature