Identification of the type II cytochrome c maturation pathway in anammox bacteria by comparative genomics.

ABSTRACT:

Background

Anaerobic ammonium oxidizing (anammox) bacteria may contribute up to 50% to the global nitrogen production, and are, thus, key players of the global nitrogen cycle. The molecular mechanism of anammox was recently elucidated and is suggested to proceed through a branched respiratory chain. This chain involves an exceptionally high number of c-type cytochrome proteins which are localized within the anammoxosome, a unique subcellular organelle. During transport into the organelle the c-type cytochrome apoproteins need to be post-translationally processed so that heme groups become covalently attached to them, resulting in mature c-type cytochrome proteins.

Results

In this study, a comparative genome analysis was performed to identify the cytochrome c maturation syste

SUBMITTER: Ferousi C 

PROVIDER: S-EPMC4222556 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature