Impact of appropriate antimicrobial therapy for patients with severe sepsis and septic shock--a quality improvement study.

ABSTRACT:

Background

There is ample literature available on the association between both time to antibiotics and appropriateness of antibiotics and clinical outcomes from sepsis. In fact, the current state of debate surrounds the balance to be struck between prompt empirical therapy and care in the choice of appropriate antibiotics (both in terms of the susceptibility of infecting organism and minimizing resistance arising from use of broad-spectrum agents). The objective of this study is to determine sepsis bundle compliance and the appropriateness of antimicrobial therapy in patients with severe sepsis and septic shock and its impact on outcomes.

Material

This study was conducted in the ICU of a tertiary care, private hospital in São Paulo, Brazil. A retrospective cohort study was c

SUBMITTER: Yokota PK 

PROVIDER: S-EPMC4222820 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature