MiR-146a rs2910164 polymorphism increases risk of gastric cancer: a meta-analysis.

ABSTRACT:

Aim

To systematically evaluate the association between the miR-146a rs2910164 polymorphism and susceptibility to gastric cancer.

Methods

A comprehensive electronic search was conducted for articles published up until January 27, 2014 in Medline (PubMed), Excerpta Medica Database (Embase), the Cochrane Library and Google Scholar. Only case-control studies published in English that evaluated the association between the miR-146a rs2910164 polymorphism and susceptibility to gastric cancer were included. Furthermore, only studies with sufficient data allowing for calculation of odds ratio (OR) and corresponding 95% confidence interval (CI) were included. These values were used in the quantitative synthesis to assess the strength of the association between the miR-146a rs2910164 p

SUBMITTER: Xie WQ 

PROVIDER: S-EPMC4223278 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature