Hospital-acquired Clostridium difficile infections: estimating all-cause mortality and length of stay.

ABSTRACT:

Background

Clostridium difficile is a health care-associated infection of increasing importance. The purpose of this study was to estimate the time until death from any cause and time until release among patients with C. difficile, comparing the burden of those in the intensive care unit (ICU) with those in the general hospital population.

Methods

A parametric mixture model was used to estimate event times, as well as the case-fatality ratio in ICU and non-ICU patients within a cohort of 609 adult incident cases of C. difficile in the Southeastern United States between 1 July 2009 and 31 December 2010.

Results

ICU patients had twice the median time to death (relative time = 1.97 [95% confidence interval (CI) = 0.96-4.01]) and nearly twice the median time to release (1

SUBMITTER: Lofgren ET 

PROVIDER: S-EPMC4224274 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature