Phylogenomics and evolutionary dynamics of the family Actinomycetaceae.

ABSTRACT: The family Actinomycetaceae comprises several important pathogens that impose serious threat to human health and cause substantial infections of economically important animals. However, the phylogeny and evolutionary dynamic of this family are poorly characterized. Here, we provide detailed description of the genome characteristics of Trueperella pyogenes, a prevalent opportunistic bacterium that belongs to the family Actinomycetaceae, and the results of comparative genomics analyses suggested that T. pyogenes was a more versatile pathogen than Arcanobacterium haemolyticum in adapting various environments. We then performed phylogenetic analyses at the genomic level and showed that, on the whole, the established members of the family Actinomycetaceae were clearly separated with high bootst

SUBMITTER: Zhao K 

PROVIDER: S-EPMC4224338 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature