Taurolidine lock is superior to heparin lock in the prevention of catheter related bloodstream infections and occlusions.

ABSTRACT:

Background and aims

Patients on home parenteral nutrition (HPN) are at risk for catheter-related complications; mainly infections and occlusions. We have previously shown in HPN patients presenting with catheter sepsis that catheter locking with taurolidine dramatically reduced re-infections when compared with heparin. Our HPN population therefore switched from heparin to taurolidine in 2008. The aim of the present study was to compare long-term effects of this catheter lock strategy on the occurrence of catheter-related bloodstream infections and occlusions in HPN patients.

Methods

Data of catheter-related complications were retrospectively collected from 212 patients who received HPN between January 2000 and November 2011, comprising 545 and 200 catheters during catheter l

SUBMITTER: Olthof ED 

PROVIDER: S-EPMC4224385 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature