Natural variants of C. elegans demonstrate defects in both sperm function and oogenesis at elevated temperatures.

ABSTRACT: The temperature sensitivity of the germ line is conserved from nematodes to mammals. Previous studies in C. briggsae and Drosophila showed that isolates originating from temperate latitudes lose fertility at a lower temperature than strains originating from tropical latitudes. In order to investigate these relationships in C. elegans, analysis of the fertility of 22 different wild-type isolates of C. elegans isolated from equatorial, tropical and temperate regions was undertaken. It was found that there are significant temperature, genotype and temperature × genotype effects on fertility but region of isolation showed no significant effect on differences in fertility. For most isolates 100% of the population maintained fertility from 20°C to 26°C, but there was a precipitous drop in the pe

SUBMITTER: Petrella LN 

PROVIDER: S-EPMC4224435 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature