Genomic analysis reveals selection for Asian genes in European pigs following human-mediated introgression.

ABSTRACT: The independent domestication of local wild boar populations in Asia and Europe about 10,000 years ago led to distinct European and Asian pig breeds, each with very different phenotypic characteristics. During the Industrial Revolution, Chinese breeds were imported to Europe to improve commercial traits in European breeds. Here we demonstrate the presence of introgressed Asian haplotypes in European domestic pigs and selection signatures on some loci in these regions, using whole genome sequence data. The introgression signatures are widespread and the Asian haplotypes are rarely fixed. The Asian introgressed haplotypes are associated with regions harbouring genes involved in meat quality, development and fertility. We identify Asian-derived non-synonymous mutations in the AHR gene that as

SUBMITTER: Bosse M 

PROVIDER: S-EPMC4225517 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature