Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study.

ABSTRACT:

Importance

Hypertension is a treatable potential cause of cognitive decline and dementia, but its greatest influence on cognition may occur in middle age.

Objective

To evaluate the association between midlife (48-67 years of age) hypertension and the 20-year change in cognitive performance.

Design, setting, and participants

The Atherosclerosis Risk in Communities cohort (1990-1992 through 2011-2013) underwent evaluation at field centers in Washington County, Maryland, Forsyth County, North Carolina, Jackson, Mississippi, and the Minneapolis, Minnesota, suburbs. Of 13 476 African American and white participants with baseline cognitive data, 58.0% of living participants completed the 20-year cognitive follow-up.

Exposures

Hypertension, prehypertension, or normal

SUBMITTER: Gottesman RF 

PROVIDER: S-EPMC4226067 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature