Association between duration of overall and abdominal obesity beginning in young adulthood and coronary artery calcification in middle age.

ABSTRACT:

Importance

Younger individuals are experiencing a greater cumulative exposure to excess adiposity over their lifetime. However, few studies have determined the consequences of long-term obesity.

Objective

To examine whether the duration of overall and abdominal obesity was associated with the presence and 10-year progression of coronary artery calcification (CAC), a subclinical predictor of coronary heart disease.

Design, setting, and participants

Prospective study of 3275 white and black adults aged 18 to 30 years at baseline in 1985-1986 who did not initially have overall obesity (body mass index [BMI] ≥30) or abdominal obesity (men: waist circumference [WC] >102 cm; women: >88 cm) in the multicenter, community-based Coronary Artery Risk Development in Young Adults

SUBMITTER: Reis JP 

PROVIDER: S-EPMC4226407 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature