Identification and functional characterization of copy number variations in diverse chicken breeds.

ABSTRACT:

Background

The detection and functional characterization of genomic structural variations are important for understanding the landscape of genetic variation in the chicken. A recently recognized aspect of genomic structural variation, called copy number variation (CNV), is gaining interest in chicken genomic studies. The aim of the present study was to investigate the pattern and functional characterization of CNVs in five characteristic chicken breeds, which will be important for future studies associating phenotype with chicken genome architecture.

Results

Using a commercial 385 K array-based comparative genomic hybridization (aCGH) genome array, we performed CNV discovery using 10 chicken samples from four local Chinese breeds and the French breed Houdan chicken. The fema

SUBMITTER: Han R 

PROVIDER: S-EPMC4226851 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature