Promoter polymorphisms in genes involved in porcine myogenesis influence their transcriptional activity.

ABSTRACT:

Background

Success of meat production and selection for improvement of meat quality is among the primary aims in animal production. Meat quality traits are economically important in swine; however, the underlying genetic nature is very complex. Therefore, an improved pork production strongly depends on identifying and studying how genetic variations contribute to modulate gene expression. Promoters are key regions in gene modulation as they harbour several binding motifs to transcription regulatory factors. Therefore, polymorphisms in these regions are likely to deeply affect RNA levels and consequently protein synthesis. In this study, we report the identification of single nucleotide polymorphisms (SNPs) in promoter regions of candidate genes involved in development, cellular dif

SUBMITTER: Bongiorni S 

PROVIDER: S-EPMC4226869 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature