Smoking in infertile women with polycystic ovary syndrome: baseline validation of self-report and effects on phenotype.

ABSTRACT:

Study question

Do women with polycystic ovary syndrome (PCOS) seeking fertility treatment report smoking accurately and does participation in infertility treatment alter smoking?

Summary answer

Self-report of smoking in infertile women with PCOS is accurate (based on serum cotinine levels) and smoking is unlikely to change over time with infertility treatment.

What is known already

Women with PCOS have high rates of smoking and it is associated with worse insulin resistance and metabolic dysfunction.

Study design, size, duration

Secondary study of smoking history from a large randomized controlled trial of infertility treatments in women with PCOS (N = 626) including a nested case-control study (N = 148) of serum cotinine levels within this cohort to validate s

SUBMITTER: Legro RS 

PROVIDER: S-EPMC4227579 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature