Irisin and exercise training in humans - results from a randomized controlled training trial.

ABSTRACT:

Background

The recent discovery of a new myokine (irisin) potentially involved in health-related training effects has gained great attention, but evidence for a training-induced increase in irisin remains preliminary. Therefore, the present study aimed to determine whether irisin concentration is increased after regular exercise training in humans.

Methods

In a randomized controlled design, two guideline conforming training interventions were studied. Inclusion criteria were age 30 to 60 years, <1 hour/week regular activity, non-smoker, and absence of major diseases. 102 participants could be included in the analysis. Subjects in the training groups exercised 3 times per week for 26 weeks. The minimum compliance was defined at 70%. Aerobic endurance training (AET) consisted

SUBMITTER: Hecksteden A 

PROVIDER: S-EPMC4228275 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature