The relationship between years of cocaine use and brain activation to cocaine and response inhibition cues.

ABSTRACT:

Aims

Functional magnetic resonance imaging research has attempted to elucidate the neurobehavioral underpinnings of cocaine dependence by evaluating differences in brain activation to cocaine and response inhibition cues between cocaine-dependent individuals and controls. This study investigated associations between task-related brain activation and cocaine use characteristics.

Design

Cross-sectional.

Setting

The Center for Biomedical Imaging at the Medical University of South Carolina, USA.

Participants

Fifty-one cocaine users (41 dependent).

Measurements

Brain activation to cocaine-cue exposure and Go No-Go tasks in six a priori selected brain regions of interest and cocaine use characteristics (i.e. cocaine dependence status, years of cocaine use, coc

SUBMITTER: Prisciandaro JJ 

PROVIDER: S-EPMC4229403 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature