Genetic variation in personality traits explains genetic overlap between borderline personality features and substance use disorders.

ABSTRACT:

Aims

To examine the genetic overlap between borderline personality features (BPF) and substance use disorders (SUDs) and the extent to which variation in personality traits contributes to this covariance.

Design

Genetic structural equation modelling was used to partition the variance in and covariance between personality traits, BPF and SUDs into additive genetic, shared and individual-specific environmental factors.

Setting

All participants were registered with the Australian Twin Registry.

Participants

A total of 3127 Australian adult twins participated in the study.

Measurements

Diagnoses of DSM-IV alcohol and cannabis abuse/dependence (AAD; CAD) and nicotine dependence (ND) were derived via computer-assisted telephone interview. BPF and five-factor m

SUBMITTER: Few LR 

PROVIDER: S-EPMC4229407 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature